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Chromosome Testing Demonstrates Effects of DU

 When radiation damages DNA, one result is an increase in the number of chromosomes which suffer breaks and recombine to give anomalous centric ring and dicentric chromosomes. These can be seen and counted using an ordinary light microscope. The method can be used to estimate historic radiation exposure over a long period of time. The results of the chromosome analysis are given in the Table. Also given are results from Chernobyl liquidators.

Group

Aberrations per 1000 metaphases scored

Mean dose over natural background

Number of metaphases scored

Gulf veterans

7

<200microGy max

1001

German controls

0.5

0

34791

Chernobyl NPP staff

5.8

300-470mGy

6015

Chernobyl controls

0.0

2mGy

3605

 The Gulf Veterans suffered greater chromosome damage than the Chernobyl NPP workers whose film badges recorded doses of 300-470 mGy.

 http://www.llrc.org/rat/ratframes.htm 

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